IL-4 induces an M2a neuroinflammatory phenotype in APP/PS1 transgenic mice. The figure shows the relative gene expression for genes representative of the M1, M2a, M2b and M2c phenotypes relative to the 18-s endogenous control. Data are shown as the average fold change (± SEM) normalized to the AAV-GFP control. *P < 0.05 between the AAV-GFP control (N = 8) and AAV-IL-4 mice (N = 6). **P < 0.01 between the AAV-GFP control and AAV-IL-4 mice.