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Table 3 Soluble and insoluble Aβ levels measured by ELISA

From: Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice

AAV injection

Soluble (pg/μg protein)

Insoluble (ng/μg protein)

 

Aβ-38

Aβ-40

Aβ-42

Aβ-38

Aβ-40

Aβ-42

GFP-AAV

30.6 ± 12.6

80.4 ± 17.7

105.6 ± 26.8

204.6 ± 82.1

191.5 ± 62.6

461.8 ± 96.0

IL-4-AAV

13.2 ± 6.7

60.4 ± 16.3

45.2 ± 8.6

83.0 ± 45.1

62.6 ± 12.1

472.2 ± 181.5

  1. Bold font indicates P < 0.05 compared to GFP-AAV of the same time point.