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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Docosahexaenoic acid (DHA): a modulator of microglia activity and dendritic spine morphology

Figure 2

DHA promotes small LB formation and normalizes LPS-induced microglial hypertrophy. A Examples of activated microglial morphologies and LB formation from control and treated organotypic hippocampal slice cultures. In the presence of DHA, more small (<0.5 μm) LBs are present compared to other conditions. In LPS-treated cultures, the activated microglia contain fewer LBs compared to others. Arrows indicate small LBs; triangles indicate larger LBs. Scale bar 10 μm. Green, Iba-I. Red, ADRP. B LB density under various treatments with various LB sizes in microglia. *p < 0.05.

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