Figure 8
Androgen receptor is mainly expressed by motor neurons in spinal cords of normal or mutant SOD1 mice. Immunohistochemical analysis of lumbar spinal cords of wild-type (WT) or sham and castrated (Cx) SOD1G93A mice at 120 days for androgen receptor (AR) and (A) GFAP or (B) CD11b. AR is mainly localised to motor neurons evident by cell size and location, but not astrocytes or microglia in WT or sham and Cx SOD1G93A mice. Scale bar = 30 μm.