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Figure 9 | Journal of Neuroinflammation

Figure 9

From: Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition

Figure 9

FK506 and tat-VIVIT did not improve spatial memory in APP/PS1 mice. Twelve-month-old male APP/PS1 mice were treated via subcutaneous delivery for 28 days with no treatment (control), vehicle DMSO, 1 mg/kg/day FK506, 0.5 mg/kg/day VIVIT, or 0.5 mg/kg/day negative control scrambled peptide, VEET (n = 6 to 8/condition). Mice were used for T-maze testing on day 28. Numbers of spontaneous alternations were averaged and graphed (±SD).

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