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Figure 4 | Journal of Neuroinflammation

Figure 4

From: Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity

Figure 4

LPS reduces both spontaneous and evoked cortical inhibition. (A) Histograms comparing the bicuculline sensitivity of the paired-pulse ratios (*P < 0.05, Scheffé’s multiple comparison). (B) Comparison of the bicuculline sensitivity of the first pulse amplitude between saline- and LPS-treated groups (N = 18 slices from five animals in each group; *P < 0.001, paired t-test). LPS, lipopolysaccharide; P1, pulse 1; P2, pulse 2.

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