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Figure 7 | Journal of Neuroinflammation

Figure 7

From: Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity

Figure 7

Pharmacological inhibition of MAO-A shows increased NE- and 5-HT-mediated effects on the paired-pulse regimen. Time series plots of pulse 1 and 2 amplitudes in the presence of the MAO-A inhibitor clorgyline illustrates an LPS-mediated enhancement of NE and 5-HT effects without altering ACh-mediated effects. (N = 18 to 24 slices from five animals in each group; *P < 0.05, unpaired t-test). 5-HT, serotonin; ACh, acetylcholine; NE, norepinephrine; LPS, lipopolysaccharide.

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