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Figure 7 | Journal of Neuroinflammation

Figure 7

From: RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells

Figure 7

Confirmation of differentially expressed genes by quantitative reverse transcription-polymerase chain reaction. (A and B) The Irf9, Irf1, Irak3, Ccl2, Ccl7, Ccl4, Ccl12, Cxcl10, Ptgs2, Irg1, and Il1a genes were significantly downregulated in JQ1-treated BV-2 microglial cells. Gene expression was normalized to GAPDH transcript levels. *P < 0.05 and **P < 0.001 compared with the control. The data represent three independent experiments. LPS, lipopolysaccharide; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.

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Journal of Neuroinflammation

ISSN: 1742-2094