Figure 5

mRNA levels for renin-angiotensin system components (renin, AT1-R, AT2-R, ACE-1, ACE-2) (A) and inflammatory cytokines (TNF-α, IL-1β, and IL-10) (B) in the PVN in each group of intact females. Values are mean ± SEM (n = 4 to 6 for each group) and expressed as a fold change relative to corresponding control. *P < 0.05 compared to control females, ^† P < 0.05 compared to central vehicle plus systemic DOCA/salt. DOCA, deoxycorticosterone acetate; icv, intracerebroventricular; PVN, paraventricular nucleus; AT, angiotensin receptor type; ACE, angiotensin-converting enzyme; IL, interleukin; TNF, tumor necrosis factor.