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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Brain endogenous angiotensin II receptor type 2 (AT2-R) protects against DOCA/salt-induced hypertension in female rats

Figure 6

Representative Western blots and quantitative comparison of protein levels for renin-angiotensin system components (renin, AT1-R, AT2-R, ACE-1, ACE-2) (A,B) and inflammatory cytokines (TNF-α, IL-1β and IL-10) (C,D) in the PVN in each group of intact females. Values are corrected by β-actin and expressed as mean ± SEM (n = 5 for each group). *P < 0.05 compared to control females, † P < 0.05 compared to central vehicle plus systemic DOCA/salt. Con, control; DOCA, deoxycorticosterone acetate; icv, intracerebroventricular; PVN, paraventricular nucleus; AT, angiotensin receptor type; ACE, angiotensin-converting enzyme; IL, interleukin; TNF, tumor necrosis factor.

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