Figure 6From: The induction of neuronal death by up-regulated microglial cathepsin H in LPS-induced neuroinflammation The function link of Cat H with microglia activation inducing neuronal apoptosis. Inflammatory cytokines induced Cat H release from microglia and enhanced its activity. Also, Cat H induced microglial activation characterized by the release of inflammatory cytokines. Cat H, alone or in combination of inflammatory cytokines, contributes to neuronal apoptosis.Back to article page