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Table 4 Level of LAG3 expression on CD19 + B cells in the presence of CBD in APC/T MOG co-cultures

From: Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells

Treatment

CD19 + LAG3 + (%)

Control

6.9 ± 0.4

CBD

7.9 ± 0.9

MOG35-55

6.0 ± 0.4

CBD + MOG35-55

5.7 ± 0.9

  1. APC/TMOG co-cultures were stimulated with MOG35-55 and CBD. The level of LAG3 was measured by flow cytometry and is expressed as mean ± SEM% of CD19+ B cells positive for LAG3. ANOVA F(3,8) = 1.8, P > 0.05 (n = 3).