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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Chronic intestinal inflammation alters hippocampal neurogenesis

Figure 6

Chronic intestinal inflammation suppresses proliferation of neuronal lineage. (A) Numbers of DCX+, Ki-67+, and DCX+/Ki-67+ cells in the SGZ of control and DSS-treated mice. For each sample, hippocampi from five mice/group were analyzed. Data are presented as a mean ± SEM. Multivariate analysis of variance (MANOVA) showed significant group effect in the cell count positive for Ki-67+, DCX+, and Ki-67+/DCX+ \( \left({\mathrm{F}}_8^3=4.33,\ \mathrm{p} = 0.0432\right); \ast \mathrm{p}\le 0.05;\ast \ast \mathrm{p}<0.01; \) (B) The confocal microscopic analysis of proliferating DCX+/Ki-67+ cells in the SGZ of control and DSS-treated mice. DCX cytoplasmic, red; Ki-67 nuclear, green. DCX, doublecortin; DSS, dextran sodium sulfate.

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