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Table 1 Demographic and clinical characteristics (combined and stratified by neurocognitive impairment)

From: Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals

Characteristics

All subjects

NC impaired

NC unimpaired

 

( n  = 107)

( n  = 58)

( n  = 49)

P value

Age, years - mean ± SD

43.7 ± 8.7

45.3 ± 9.3

41.8 ± 7.6

0.033

Gender, male - N (%)

93 (86.9%)

52 (89.7%)

42 (85.7%)

0.406

Race

    

 White - N (%)

59 (55.1%)

31 (53.5%)

28 (57.1%)

0.962

 Black

34 (31.8%)

18 (31.0%)

16 (32.7%)

 

 Other

14 (13.1%)

9 (15.5%)

5 (10.2%)

 

AIDS - N (%)

68 (63.6%)

38 (65.5%)

30 (61.2%)

0.554

ART use - N (%)

84 (78.5%)

45 (77.6%)

39 (79.6%)

0.956

Plasma HIV VL undetectable - N (%)

53 (49.5%)

29 (50.0%)

24 (50.0%)

0.838

CSF HIV VL undetectable - N (%)

79 (73.8%)

44 (75.9%)

36 (73.5%)

0.910

Current CD4+ count (<200 cells/μL) - N (%)

22 (20.8%)

9 (15.5%)

13 (26.5%)

0.160

Current CD4+ count - median (IQR)

405 (216 to 582)

435 (260 to 589)

360 (175 to 531)

0.247

Albumin (<5 g/dL)

72 (67.9%)

37 (64.9%)

35 (71.4%)

0.474

Alcohol dependence - N (%)

25 (23.2%)

12 (20.7%)

13 (26.5%)

0.514

HGB (mean ± SD)

14.1 ± 1.5

14.1 ± 1.6

14.1 ± 1.4

0.882

AST - median (IQR)

30 (23 to 37)

31 (24 to 39)

30 (22 to 36)

0.673

ALT - median (IQR)

33 (22 to 43)

36 (23 to 43)

30 (22 to 40)

0.298

Body mass index (BMI)

   

0.290

BMI ≤ 25

45 (42.1%)

24 (41.4%)

21 (42.9%)

 

25 < BMI < 30

45 (42.1%)

22 (37.9%)

23 (46.9%)

 

BMI ≥ 30

17 (15.8%)

12 (20.7%)

5 (10.2%)

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