Fig. 1

EA reduced loss of body weight, delayed paralysis onset, and increased lifespan in A53T mice. a Schematic diagram illustrating the experimental timeline for behavioral tests and EA treatments. b Effects of EA on the loss of body weight in A53T mice (n = 10 per group). Note a significant loss of body weight starting at 70 days in A53T mice. EA was able to reverse the loss at three testing days (80, 90, and 100 days). c Effects of EA on the onset of paralysis observed in A53T mice (n = 15 per group). d Effects of EA on survival rate of A53T mice (n = 15 per group). Data in Fig. 1b are expressed as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs. nTg group. # P < 0.05, ## P < 0.01 vs. A53T group