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Figure 2 | Journal of Neuroinflammation

Figure 2

From: Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia

Figure 2

Effect of aging on microglial proliferation and cell infiltration. Number of BrdU+ (A) and BrdU+/Iba1+ (B) cells in the peri-infarct area (cortex) at 7 and 14 days after MCAO in young and aged mice. The number of BrdU+ and BrdU+/Iba1+ cells (microglial/macrophages cells) was quantified on digitalized confocal images (see Methods). Representative images of Iba1+ cells in the ipsilesional peri-infarct hemispheres in young and aged mice. Scale bar = 50 μm (C). MCAO, middle cerebral artery occlusion.

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