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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation

Fig. 6

Leukocyte recruitment and the expression of P-selectin and VCAM-1 in the WT, CXCR2−/−, and chimeric mice. a Chimeric mice were generated by transferring bone marrow cells between WT and CXCR2−/− mice. b Intravital microscopy was performed on WT, CXCR2−/−, and chimeric mice, 4 h after i.c.v. LPS injection. The number of rolling and adherent leukocytes is presented as the mean ± SEM. c The expression of P-selectin and VCAM-1 in the WT, CXCR2−/−, and chimeric mice was compared by Western blotting, n = 4 mice per group. Data are presented as the means ± SEM, *P < 0.05; **P < 0.01

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