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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer’s disease

Fig. 7

Comparative analysis of immune populations in APPPS1 and WT mice between 4 and 7 months of age. Representative images from brain cortex of APPPS1 mice (a, c) and numbers of CD3+ T cells (b) or CD11b+ cells (d) in the brain parenchyma of WT and APPPS1 mice. (e) Percentage of CD3+ T cells in the spleen analyzed by flow cytometry. (f) Quantification by ELISA of Aβ load in the brain. Mean ± SD (three to five mice/group). Results are representative of two independent experiments. Mann–Whitney U test, **p ≤ 0.01, ***p ≤ 0.001

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Journal of Neuroinflammation

ISSN: 1742-2094