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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis

Fig. 5

Administration of hAECs increases the total number of Tregs and naïve CD4+ T cells in the periphery. Mononuclear cells were isolated from the lymph nodes and spleen at day 37, and the proportion and number of Tregs or naïve CD4+ T cells was analyzed by flow cytometry. a Total cell number in the lymph nodes. b Proportion of gated lymphocytes that are CD4 + CD25 + Foxp3+ Tregs in the lymph nodes. c Total Treg numbers in the lymph nodes. d Total cell number in the spleen. e Proportion of gated lymphocytes that are CD4 + CD25 + Foxp3+ Tregs in the spleen. f Total Treg numbers in the spleen. g Proportion of CD4+ that are naïve (CD62LhiCD44lo) T cells in the spleen. h Total number of CD4+ naïve (CD62LhiCD44lo) T cells in the spleen. (n = 6, *P < 0.05 compared to PBS)

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Journal of Neuroinflammation

ISSN: 1742-2094