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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury

Fig. 4

M1 and M2 macrophage effects on astrocyte reactive expression pattern. a In primary astrocytes, qPCR for gene expression associated with a reactive astrocyte phenotype shows opposite effects following stimulation with M1 or M2 macrophage-conditioned medium. Expression of most genes is upregulated following M1 stimulation and downregulated following M2 stimulation. b In spinal cord organotypic cultures, very similar gene expression changes are seen

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