Skip to main content
Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Fig. 3

The concentration of tryptophan in serum is reduced after TBI. The concentration of tryptophan in serum samples of TBI patients was measured from the day of hospital admission (day 0) to day 5 after injury and compared to the control serum. Significant decrease in serum TRP levels were observed between days 0 and 4; there was no statistical difference at day 5 to control levels, but median concentration at day 5 (36.29 μM) was similar to day 4 (35.6 μM). Data is shown as daily median with 25–75 percentile. Asterisks indicate significant differences (p < 0.05) between TBI and control using one-way ANOVA followed by Dunnett’s multiple comparison as post hoc. TBI patients: n = 25–28 per time point; control group: n = 9–11

Back to article page