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Table 2 Details of the 16 trauma and 10 control cases

From: Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Case

Age (years)

Sex

Cause of injury

PMI (h)

Cause of death

Survival time

1

51.1

M

Motor vehicle accident

60

Brain + multiple injuries

<17 min

2

78.7

M

Nursing home accident

45

Brain injury

<17 min

3

27

M

Suicide

84

Brain + multiple injuries

<17 min

4

18.3

M

Motor vehicle accident

79

Brain + multiple injuries

<17 min

5

57.9

F

Motor vehicle accident

87

Brain + multiple injuries

<17 min

6

49

M

Motor vehicle accident

107

Brain + multiple injuries

<17 min

7

34.7

M

Motorbike accident

66

Brain + multiple injuries

<17 min

8

21.5

M

Motor vehicle accident

100

Brain injury

<17 min

9

57.6

F

Motor vehicle accident

97

Brain injury

<17 min

10

46.0

M

Fall

129

Brain injury

6 h

11

56.3

M

Motor vehicle accident

65

Brain injury

8 h

12

64.6

M

Fall

61

Brain injury

8 h

13

75.9

M

Staircase fall

89

Brain injury

10 h

14

59.6

F

Motor vehicle accident

80

Brain injury

35 h

15

61.7

M

Fall

40

Brain injury

93 h

16

38.9

F

Staircase fall

101

Brain injury

122 h

17

16

M

-

-

Suicide by hanging

-

18

48.7

M

-

50

Cardiac failure

-

19

51.6

M

-

64

Asthma

-

20

52.3

M

-

52

Cardiomyopathy

-

21

59.6

M

-

43

Pulmonary embolism

-

22

64.1

M

-

24

Ischaemic heart disease

-

23

66.9

M

-

10

Pneumonia

-

24

64.4

M

-

24

Pulmonary embolism

-

25

77.5

M

-

53

Myocardial infarction

-

26

60

F

-

48

Myocardial infarction

-

  1. Cases 1–9: cases with a survival time between 0 and 17 min; cases 10–16: cases with a survival time between 6 and 261 h; cases 17–26: control cases. All brains were obtained at autopsy
  2. PMI post-mortem interval (time between death and brain retrieval), M male, F female