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Table 2 Details of the 16 trauma and 10 control cases

From: Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Case Age (years) Sex Cause of injury PMI (h) Cause of death Survival time
1 51.1 M Motor vehicle accident 60 Brain + multiple injuries <17 min
2 78.7 M Nursing home accident 45 Brain injury <17 min
3 27 M Suicide 84 Brain + multiple injuries <17 min
4 18.3 M Motor vehicle accident 79 Brain + multiple injuries <17 min
5 57.9 F Motor vehicle accident 87 Brain + multiple injuries <17 min
6 49 M Motor vehicle accident 107 Brain + multiple injuries <17 min
7 34.7 M Motorbike accident 66 Brain + multiple injuries <17 min
8 21.5 M Motor vehicle accident 100 Brain injury <17 min
9 57.6 F Motor vehicle accident 97 Brain injury <17 min
10 46.0 M Fall 129 Brain injury 6 h
11 56.3 M Motor vehicle accident 65 Brain injury 8 h
12 64.6 M Fall 61 Brain injury 8 h
13 75.9 M Staircase fall 89 Brain injury 10 h
14 59.6 F Motor vehicle accident 80 Brain injury 35 h
15 61.7 M Fall 40 Brain injury 93 h
16 38.9 F Staircase fall 101 Brain injury 122 h
17 16 M - - Suicide by hanging -
18 48.7 M - 50 Cardiac failure -
19 51.6 M - 64 Asthma -
20 52.3 M - 52 Cardiomyopathy -
21 59.6 M - 43 Pulmonary embolism -
22 64.1 M - 24 Ischaemic heart disease -
23 66.9 M - 10 Pneumonia -
24 64.4 M - 24 Pulmonary embolism -
25 77.5 M - 53 Myocardial infarction -
26 60 F - 48 Myocardial infarction -
  1. Cases 1–9: cases with a survival time between 0 and 17 min; cases 10–16: cases with a survival time between 6 and 261 h; cases 17–26: control cases. All brains were obtained at autopsy
  2. PMI post-mortem interval (time between death and brain retrieval), M male, F female