Fig. 5
From: Functional differences between microglia and monocytes after ischemic stroke
Relationship between TNF production and phagocytic activity of microglia after stroke. A representative dot plot shows the relationship between microglial TNF production and phagocytic activity at 24 h (a). The percentage of TNF+ microglia is significantly higher in the phagocytic subset of microglia compared to the non-phagocytic subset (N = 5/group; b). A positive correlation was found between the MFI of TNF expression in microglia and number of beads they phagocytosed after stroke (c). Cell-specific FMO controls were used to determine positive gating. Error bars show mean SEM. Abbreviation: SEM standard error of the mean, SSC side scatter, MFI mean fluorescence intensity, a.u.i. arbitrary units of intensity. *p < 0.05