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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia

Fig. 4

Effect of IL-1Ra on motor behavior of LPS+HI-exposed rats at P14 and P120. IL-1Ra decreased the circling score of animals 48 h after the exposition to LPS+HI (a). At P120, IL-1Ra decreased the distance traveled in the open field (b), right/left ratio in Turning in Alley (c), and latency to upswing (d) in elevated body swing tests of rats exposed to LPS+HI. Error bars represent means ± SEM, ten to twenty animals per conditions, unpaired t test with Welch correction, * p ≤ 0.05, *** p ≤ 0.001. Abbreviations: m meter, sec second

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