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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Neuronal self-injury mediated by IL-1β and MMP-9 in a cerebral palsy model of severe neonatal encephalopathy induced by immune activation plus hypoxia-ischemia

Fig. 5

Expressions of NLRP1 and NLRP3 in neocortical neurons. IF staining of co-localizing NeuN+NLRP1+ neurons (arrowheads) in the neocortex at P12 in control rats (a). IF staining of co-localizing Iba1+NLRP3+ macrophage/microglia (arrowheads) in the neocortex at P40 in control rats (b). Scale bar = 10 μm, three to four animals per conditions, unpaired t test with Welch correction, ** p ≤ 0.01, **** p ≤ 0.0001. Abbreviations: NLRP nod-like receptor protein, NeuN neuronal nuclei, Iba-1 ionized calcium-binding adapter molecule 1

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Journal of Neuroinflammation

ISSN: 1742-2094