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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Caspase-1 inhibitor ameliorates experimental autoimmune myasthenia gravis by innate dendric cell IL-1-IL-17 pathway

Fig. 1

Effects of caspase-1 inhibitor on the phenotype and IL-1β of DCs in vitro. DC from Lewis rats were stimulated with LPS (100 ng/ml) and cultured with the caspase-1 inhibitor Ac-YVAD-cmk (8 μM) for 48 h. Expression of CD80, CD86, MHC class II, and IL-1β from spleen DC (a) and bone marrow DC (b) were assessed by FACS. Data are expressed as mean ± SD of n = 3 rats/group representative of three independent experiments (*p < 0.05)

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