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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes

Fig. 5

Colocalization of both subunits of IL-22 receptor on primary astrocytes. a Flow cytometry experiments show the expression of both subunits of the IL-22 receptor, IL-10R2, and IL-22R1 (in red), on human primary astrocytes (HA) as compared to their isotype control counterparts (in black). b–d By immunofluorescent confocal microscopy, there is a colocalization of GFAP (green) with IL-10R2 (red) (b) and with IL-22R1 (red) (c) as well as of IL-10R2 (green) with IL-22R1 (red) (d). The colocalization appears is depicted in yellow (arrows, MERGE). DAPI is represented in blue and not included in MERGE overlay. Bars, 50 μm

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