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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis

Fig. 2

Levels of IFN-γ and IL-17A are downregulated in EAE mice treated with rhPDCD5. a, b Serum samples were collected from mice treated with OVA or rhPDCD5 prophylactically and therapeutically on day 25 after immunization, and cytokine concentrations were determined by ELISA. Data are means ± SEM (n = 10). c, d Draining lymph node cells were obtained from indicated mice and cultured with or without MOG35–55 (20 μg/ml) for 48 h, and the cytokine levels in the culture supernatants were determined by ELISA. Data are means ± SEM (n = 10). *P < 0.05, **P < 0.005

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