TY - JOUR AU - Akiyama, H. PY - 2000 DA - 2000// TI - Inflammation in neurodegenerative disease JO - Neurobiol Aging VL - 21 UR - https://doi.org/10.1016/S0197-4580(00)00124-X DO - 10.1016/S0197-4580(00)00124-X ID - Akiyama2000 ER - TY - JOUR AU - Cameron, B. AU - Landreth, G. E. PY - 2010 DA - 2010// TI - Inflammation, microglia and Alzheimer’s disease JO - Neurobiol Dis VL - 37 UR - https://doi.org/10.1016/j.nbd.2009.10.006 DO - 10.1016/j.nbd.2009.10.006 ID - Cameron2010 ER - TY - JOUR AU - Grammas, P. PY - 2011 DA - 2011// TI - Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer’s disease JO - J Neuroinflamm VL - 8 UR - https://doi.org/10.1186/1742-2094-8-26 DO - 10.1186/1742-2094-8-26 ID - Grammas2011 ER - TY - JOUR AU - McGeer, P. L. AU - McGeer, E. G. PY - 2006 DA - 2006// TI - NSAIDS and Alzheimer disease: epidemiological, animal model and clinical studies JO - Neurobiol Aging VL - 28 UR - https://doi.org/10.1016/j.neurobiolaging.2006.03.013 DO - 10.1016/j.neurobiolaging.2006.03.013 ID - McGeer2006 ER - TY - JOUR AU - Streit, W. J. AU - Conde, J. R. AU - Harrison, J. K. PY - 2001 DA - 2001// TI - Chemokines and Alzheimer’s disease JO - Neurobiol Aging VL - 22 UR - https://doi.org/10.1016/S0197-4580(01)00290-1 DO - 10.1016/S0197-4580(01)00290-1 ID - Streit2001 ER - TY - JOUR AU - Ryu, J. K. AU - Mclarnon, J. G. PY - 2008 DA - 2008// TI - Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-α in an animal model of inflamed Alzheimer’s disease brain JO - Neurobiol Dis VL - 29 UR - https://doi.org/10.1016/j.nbd.2007.08.019 DO - 10.1016/j.nbd.2007.08.019 ID - Ryu2008 ER - TY - JOUR AU - McLarnon, J. G. PY - 2012 DA - 2012// TI - Microglial chemotactic signaling factors in Alzheimer’s disease JO - Am J Neurodegener Dis VL - 1 ID - McLarnon2012 ER - TY - JOUR AU - Xia, M. AU - Hyman, B. T. PY - 2012 DA - 2012// TI - Chemokines/chemokine receptors in the central nervous system and Alzheimer’s disease JO - J Neuro Virology VL - 5 ID - Xia2012 ER - TY - JOUR AU - Miller, R. J. AU - Rostene, W. AU - Aportis, E. AU - Banisadr, E. AU - Bibar, K. AU - Milligan, E. D. PY - 2008 DA - 2008// TI - Chemokine action in the nervous system JO - J Neurosci VL - 28 UR - https://doi.org/10.1523/JNEUROSCI.3588-08.2008 DO - 10.1523/JNEUROSCI.3588-08.2008 ID - Miller2008 ER - TY - JOUR AU - Walker, D. G. AU - Lue, L. F. AU - Beach, T. G. PY - 2001 DA - 2001// TI - Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia JO - Neurobiol Aging VL - 22 UR - https://doi.org/10.1016/S0197-4580(01)00306-2 DO - 10.1016/S0197-4580(01)00306-2 ID - Walker2001 ER - TY - JOUR AU - Lue, L. F. AU - Rydel, R. AU - Brigham, E. AU - Yang, L. B. AU - Hampel, H. AU - Murphy, G. M. PY - 2001 DA - 2001// TI - Inflammatory repertoire of Alzheimer’s disease and nondemented elderly microglia in vitro JO - Glia VL - 35 UR - https://doi.org/10.1002/glia.1072 DO - 10.1002/glia.1072 ID - Lue2001 ER - TY - JOUR AU - Galimberti, D. AU - Schoonenboom, N. AU - Scheltens, P. AU - Fenoglio, C. AU - Bouwman, F. AU - Venturelli, E. PY - 2006 DA - 2006// TI - Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease JO - Arch Neurol VL - 63 UR - https://doi.org/10.1001/archneur.63.4.538 DO - 10.1001/archneur.63.4.538 ID - Galimberti2006 ER - TY - JOUR AU - Franciosi, S. AU - Ryu, J. K. AU - Kim, S. U. AU - McLarnon, J. G. PY - 2005 DA - 2005// TI - IL-8 enhancement of amyloid- beta (Abeta1-42)-induced expression and production of proinflammatory cytokines and COX-2 in cultured human microglia JO - J Neuroimmunol VL - 159 UR - https://doi.org/10.1016/j.jneuroim.2004.10.006 DO - 10.1016/j.jneuroim.2004.10.006 ID - Franciosi2005 ER - TY - JOUR AU - Xia, M. AU - Qin, S. AU - McNamara, M. AU - Mackay, C. AU - Hyman, B. T. PY - 1997 DA - 1997// TI - Interleukin-8 receptor immunoreactivity in brain and neuritic plaques of Alzheimer’s disease JO - Am J Pathol VL - 150 ID - Xia1997 ER - TY - JOUR AU - Stevenson, C. S. AU - Coote, K. AU - Webster, R. AU - Johnston, H. AU - Atherton, H. C. AU - Nicholls, A. PY - 2005 DA - 2005// TI - Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect JO - Am J Physiol Lung Cell Mol Physiol VL - 288 UR - https://doi.org/10.1152/ajplung.00317.2004 DO - 10.1152/ajplung.00317.2004 ID - Stevenson2005 ER - TY - JOUR AU - Gorio, A. AU - Madaschi, L. AU - Zadra, G. AU - Marfia, G. AU - Cavalieri, B. AU - Bertini, R. PY - 2007 DA - 2007// TI - Reparixin, an inhibitor of CXCR2 function, attenuates inflammatory responses and promotes recovery of function after traumatic lesion to the spinal cord JO - J Pharmacol Exp Thera VL - 322 UR - https://doi.org/10.1124/jpet.107.123679 DO - 10.1124/jpet.107.123679 ID - Gorio2007 ER - TY - JOUR AU - Valles, A. AU - Grijpink-Ongering, L. AU - Bree, F. M. AU - Tuinstra, T. AU - Ronken, E. PY - 2006 DA - 2006// TI - Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuron survival JO - Neurobiol Dis VL - 22 UR - https://doi.org/10.1016/j.nbd.2005.11.015 DO - 10.1016/j.nbd.2005.11.015 ID - Valles2006 ER - TY - JOUR AU - Jamieson, T. AU - Clarke, M. AU - Steele, C. W. AU - Samuel, M. S. AU - Neumann, J. AU - Jung, A. PY - 2012 DA - 2012// TI - Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis JO - J Clin Invest VL - 122 UR - https://doi.org/10.1172/JCI61067 DO - 10.1172/JCI61067 ID - Jamieson2012 ER - TY - JOUR AU - Traves, S. L. AU - Smith, S. J. AU - Barnes, P. J. AU - Donnelly, L. E. PY - 2004 DA - 2004// TI - Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2 JO - J Leuokocyte Biol VL - 76 UR - https://doi.org/10.1189/jlb.1003495 DO - 10.1189/jlb.1003495 ID - Traves2004 ER - TY - JOUR AU - Schwab, C. AU - Yu, S. AU - Wong, W. AU - McGeer, E. C. AU - McGeer, P. L. PY - 2013 DA - 2013// TI - GAD65, GAD67 and GABAT immunostaining in human brain and apparent GAD65 loss in Alzheimer’s disease JO - J Alzheimer Dis VL - 33 ID - Schwab2013 ER - TY - JOUR AU - Braak, H. AU - Braak, K. PY - 1991 DA - 1991// TI - Neuropathological stageing of Alzheimer-related changes JO - Acta Neuropathol VL - 82 UR - https://doi.org/10.1007/BF00308809 DO - 10.1007/BF00308809 ID - Braak1991 ER - TY - JOUR PY - 1997 DA - 1997// TI - Consensus recommendations for the post-mortem diagnosis of Alzheimer’s disease. National Institute of Aging and Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer’s disease JO - Neurobiol Aging VL - 18 UR - https://doi.org/10.1016/S0197-4580(97)00057-2 DO - 10.1016/S0197-4580(97)00057-2 ID - ref22 ER - TY - JOUR AU - Miklossy, J. AU - Arai, T. AU - Guo, J. P. AU - Klegeris, A. AU - Yu, S. AU - McGeer, E. G. PY - 2006 DA - 2006// TI - LRRK2 expression in normal and pathological human brain and in human cell lines JO - J Neuropath Exp Neurol VL - 65 UR - https://doi.org/10.1097/01.jnen.0000235121.98052.54 DO - 10.1097/01.jnen.0000235121.98052.54 ID - Miklossy2006 ER - TY - JOUR AU - Franciosi, S. AU - Ryu, J. K. AU - Choi, H. B. AU - Radov, L. AU - Kim, S. U. AU - McLarnon, J. G. PY - 2006 DA - 2006// TI - Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signalling and functional responses in human microglia JO - J Neurosci VL - 26 UR - https://doi.org/10.1523/JNEUROSCI.2490-06.2006 DO - 10.1523/JNEUROSCI.2490-06.2006 ID - Franciosi2006 ER - TY - JOUR AU - Ryu, J. K. AU - McLarnon, J. G. PY - 2009 DA - 2009// TI - A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer’s disease brain JO - J Cell Mol Med VL - 13 UR - https://doi.org/10.1111/j.1582-4934.2008.00434.x DO - 10.1111/j.1582-4934.2008.00434.x ID - Ryu2009 ER - TY - JOUR AU - Ryu, J. K. AU - Cho, T. AU - Choi, H. B. AU - Wang, Y. T. AU - McLarnon, J. G. PY - 2009 DA - 2009// TI - Microglial VEGF receptor response is an integral chemotactic component in Alzheimer’s disease pathology JO - J Neurosci VL - 29 UR - https://doi.org/10.1523/JNEUROSCI.2888-08.2009 DO - 10.1523/JNEUROSCI.2888-08.2009 ID - Ryu2009 ER - TY - JOUR AU - Overbeek, S. A. AU - Henricks, P. A. J. AU - Srienc, A. I. AU - Koelink, P. J. AU - Kruijf, P. AU - Lim, H. D. PY - 2011 DA - 2011// TI - N-acetylated proline-glycine-proline induced G-protein dependent chemotaxis of neutrophils independent of CXCL8 release JO - Eur J Pharmacol VL - 668 UR - https://doi.org/10.1016/j.ejphar.2011.03.022 DO - 10.1016/j.ejphar.2011.03.022 ID - Overbeek2011 ER - TY - JOUR AU - Bindokas, V. P. AU - Jordan, J. AU - Lee, C. C. AU - Miller, R. J. PY - 1996 DA - 1996// TI - Superoxide production in rat hippocampal neurons: selective imaging with hydroethidine JO - J Neurosci VL - 16 ID - Bindokas1996 ER - TY - JOUR AU - Choi, H. B. AU - Ryu, J. K. AU - Kim, S. U. AU - McLarnon, J. G. PY - 2007 DA - 2007// TI - Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain JO - J Neurosci VL - 27 UR - https://doi.org/10.1523/JNEUROSCI.5417-06.2007 DO - 10.1523/JNEUROSCI.5417-06.2007 ID - Choi2007 ER - TY - JOUR AU - McLarnon, J. G. AU - Ryu, J. K. PY - 2008 DA - 2008// TI - Relevance of Aβ1–42 intrahippocampal injection as an animal model of inflamed Alzheimer’s disease brain JO - Curr Alz Res VL - 5 UR - https://doi.org/10.2174/156720508785908874 DO - 10.2174/156720508785908874 ID - McLarnon2008 ER - TY - JOUR AU - McLarnon, J. G. AU - Ryu, J. K. AU - Walker, D. G. AU - Choi, H. B. PY - 2006 DA - 2006// TI - Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid beta peptide-treated microglia and in peptide-injected rat hippocampus JO - J Neuropathol Exp Neurol VL - 65 UR - https://doi.org/10.1097/01.jnen.0000240470.97295.d3 DO - 10.1097/01.jnen.0000240470.97295.d3 ID - McLarnon2006 ER - TY - JOUR AU - Sayre, L. M. AU - Zelasko, D. A. AU - Harris, P. L. AU - Perry, G. AU - Salomon, R. G. AU - Smith, M. A. PY - 1997 DA - 1997// TI - 4- hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer’s disease JO - J Neurochem VL - 68 UR - https://doi.org/10.1046/j.1471-4159.1997.68052092.x DO - 10.1046/j.1471-4159.1997.68052092.x ID - Sayre1997 ER - TY - JOUR AU - Forero, D. A. AU - Casadesus, G. AU - Perry, G. AU - Arboleda, H. PY - 2006 DA - 2006// TI - Synaptic dysfunction and oxidative stress in Alzheimer’s disease: emerging mechanisms JO - J Cell Mol Med VL - 10 UR - https://doi.org/10.1111/j.1582-4934.2006.tb00439.x DO - 10.1111/j.1582-4934.2006.tb00439.x ID - Forero2006 ER - TY - JOUR AU - Butterfield, D. A. AU - Griffin, S. AU - Munch, G. AU - Pasinetti, G. M. PY - 2002 DA - 2002// TI - Amyloid β-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer’s disease brain exists JO - J Alz Dis VL - 4 ID - Butterfield2002 ER - TY - JOUR AU - McDonald, D. R. AU - Brunden, K. R. AU - Landreth, G. E. PY - 1997 DA - 1997// TI - Amyloid fibrils activate tyrosine kinase-dependent signalling and superoxide production in microglia JO - J Neurosci VL - 17 ID - McDonald1997 ER - TY - JOUR AU - Wang, Q. AU - Rowan, M. J. AU - Anwyl, R. PY - 2004 DA - 2004// TI - β-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide JO - J Neurosci VL - 24 UR - https://doi.org/10.1523/JNEUROSCI.0233-04.2004 DO - 10.1523/JNEUROSCI.0233-04.2004 ID - Wang2004 ER - TY - JOUR AU - Combs, C. K. PY - 2009 DA - 2009// TI - Inflammation and microglial actions in Alzheimer’s disease JO - J Neuroimmune Pharmacol VL - 4 UR - https://doi.org/10.1007/s11481-009-9165-3 DO - 10.1007/s11481-009-9165-3 ID - Combs2009 ER - TY - JOUR AU - Hashioka, S. AU - McLarnon, J. G. AU - Ryu, J. K. AU - Abd-el-aziz, A. AU - Neeland, E. AU - Klegeris, A. PY - 2011 DA - 2011// TI - Pyrazole compound 2-MBAPA as a novel inhibitor of microglial activation and neurotoxicity in vitro and in vivo JO - J Alzheimer’s Dis VL - 27 ID - Hashioka2011 ER - TY - JOUR AU - Jantaratnotai, N. AU - Schwab, C. AU - Ryu, J. K. AU - McGeer, P. L. AU - McLarnon, J. G. PY - 2010 DA - 2010// TI - Converging perturbed microvasculature and microglial clusters characterize Alzheimer disease brain JO - Curr Alz Res VL - 7 UR - https://doi.org/10.2174/156720510793499039 DO - 10.2174/156720510793499039 ID - Jantaratnotai2010 ER - TY - JOUR AU - Wyss-Coray, T. PY - 2006 DA - 2006// TI - Inflammation in Alzheimer disease: driving force, bystander or beneficial response JO - Nat Med VL - 12 ID - Wyss-Coray2006 ER - TY - JOUR AU - Simard, A. R. AU - Soulet, D. AU - Gowing, G. AU - Julien, J. P. AU - Rivest, S. PY - 2006 DA - 2006// TI - Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer’s disease JO - Neuron VL - 49 UR - https://doi.org/10.1016/j.neuron.2006.01.022 DO - 10.1016/j.neuron.2006.01.022 ID - Simard2006 ER - TY - STD TI - Weitz TM, Town T. Microglia in Alzheimer disease: it’s all about context. Int J Alz Dis. 2012. doi:10.1155/2012/314185. ID - ref42 ER - TY - JOUR AU - Khoury, J. AU - Toft, M. AU - Hickman, S. E. AU - Means, T. K. AU - Terada, K. AU - Geula, C. PY - 2007 DA - 2007// TI - Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease JO - Nat Med VL - 13 UR - https://doi.org/10.1038/nm1555 DO - 10.1038/nm1555 ID - Khoury2007 ER - TY - JOUR AU - Fuhrmann, M. AU - Bittner, T. AU - Jung, C. K. AU - Burgold, S. AU - Page, R. M. AU - Mitteregger, G. PY - 2010 DA - 2010// TI - Microglial Cx3cr1 knockout prevents neuronal loss in a mouse model of Alzheimer’s disease JO - Nat Neurosci VL - 13 UR - https://doi.org/10.1038/nn.2511 DO - 10.1038/nn.2511 ID - Fuhrmann2010 ER - TY - JOUR AU - Hardy, J. AU - Selkoe, D. J. PY - 2002 DA - 2002// TI - The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics JO - Science VL - 297 UR - https://doi.org/10.1126/science.1072994 DO - 10.1126/science.1072994 ID - Hardy2002 ER - TY - JOUR AU - Zlokovic, B. V. PY - 2010 DA - 2010// TI - Neurodegeneration and the neurovascular unit JO - Nat Med VL - 16 UR - https://doi.org/10.1038/nm1210-1370 DO - 10.1038/nm1210-1370 ID - Zlokovic2010 ER -