Fig. 3
From: Bee venom ameliorates lipopolysaccharide-induced memory loss by preventing NF-kappaB pathway
Inhibitory effect of BV on LPS-induced expression of Aβ1-42 in both GFAP and IBA-1-positive mice brain. Staining was performed in 30-μm-thick sections of mice brain. Confocal microscope observation was performed as described in the Methods section. Immunostaining of GFAP (green) and Aβ1−42 (red) protein in the hippocampus was performed with specific primary antibodies, and fluorescence was developed using Alexa 488-conjugated anti-goat and Alexa 568-conjugated anti-rabbit secondary antibodies (a). IBA-1 (red) and Aβ1−42 (green) protein in the hippocampus was performed with specific primary antibodies, and fluorescence was developed using Alexa 488-conjugated anti-mouse and Alexa 568-conjugated anti-rabbit secondary antibodies (b). Values are presented as mean ± S.E. from eight mice. # p < 0.05 compared to control, *p < 0.05 compared to LPS