Fig. 8From: TNF-dependent regulation and activation of innate immune cells are essential for host protection against cerebral tuberculosisTNF regulates synthesis of IL-1β and IL-12p70. TNFf/f (black), NsTNF−/− (grey) and TNF−/− (clear) mice were infected with M. tuberculosis H37Rv infection at a dose of 1 × 103–1 × 104 CFUs/brain by intracerebral inoculation. a TNF, b IL-1β and c IL-12p70 cerebral concentrations were measured by ELISA at 3 weeks post-infection. Data (mean ± SEM of the CFUs of 5–6 mice per time point) are representative of repeat experiments. *p ≤ 0.05Back to article page