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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: Pro-inflammatory TNFα and IL-1β differentially regulate the inflammatory phenotype of brain microvascular endothelial cells

Fig. 8

Following the acute reduction in barrier resistance, TNFα and IL-1β mediate a progressive and sustained strengthening of the endothelial barrier. The longer temporal profile measured by ECIS reveals that, following the initial small suppression of barrier resistance, there is a pronounced increase in barrier resistance from both IL-1β and TNFα, which occurs in a time- and concentration-dependent manner. Each curve represents the mean of 4–6 wells

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