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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Tumor necrosis factor-α enhances voltage-gated Na+ currents in primary culture of mouse cortical neurons

Fig. 5

Effects of TNF-α on spike. a, b Traces showing representative recordings of action potentials. Threshold of action potential was significantly lower in the TNF-α group than in the control group. c Histogram showing the action potential threshold in the control and TNF-α groups, (*P < 0.05, n = 10 in each group (Student’s t-test). d and e Representative recordings of firing rate of action potential in response to current injection (500 pA, 1 s) in the control and TNF-α (100 pg/ml for 24 h) groups. f Histogram showing the firing rate in the control and TNF-α (100 pg/ml for 24 h) groups. *P < 0.05, Student’s t-test (n = 8 in each group)

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Journal of Neuroinflammation

ISSN: 1742-2094