Fig. 4
From: Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis
Expression of T cell receptor (TCR) Vδ1 and Vδ2 chains by γδ T cells in brain-infiltrating lymphocytes (BILs) and peripheral blood mononuclear cells (PBMCs) from two RE patients. BILs and PBMCs from two RE cases were stained with CD3, CD4, CD8, TCR αβ, TCR Vδ1-, and TCR Vδ2-specific antibodies. CD3+ CD4− CD8− PBMCs are predominantly Vδ2+ (76.7 and 79.8 % for RECP26 and RECP33, respectively), whereas most CD3+ CD4− CD8− BILs express Vδ1 (89.8 and 97.1 % for RECP26 and RECP33, respectively). The number of CD3+ BILs gated was 1887 for RECP26 and 1516 for RECP33