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Table 3 Discriminatory power for patient clustering of genes expressed in CSF cells

From: Immune and Epstein-Barr virus gene expression in cerebrospinal fluid and peripheral blood mononuclear cells from patients with relapsing-remitting multiple sclerosis

Genes

AUC (95 % CI)

MHC class II

1.0 (1.0–1.0)

CD4

0.97 (0.91–1.0)

CD68

0.94 (0.84–1.0)

OAS1

0.92 (0.83–1.0)

COX-2

0.87 (0.72–1.0)

NAMPT

0.85 (0.68–1.0)

IL-1β

0.85 (0.63–1.0)

  1. ROC curve analysis was performed to define the accuracy of genes differentially expressed in CSF cells to discriminate between cluster 1 and cluster 2 patients; cluster 3 patient was not considered
  2. AUC area under ROC curve, CI confidence interval