Fig. 3

Longitudinal study of the NTZ-treated patients. a Thirty-five NTZ patients were analysed three times during treatment: first, second and third sampling. The overall results of the first sample were divided into three regions. High, low and medium indicate respectively the region above the 75th percentile (H; black square), that below the 25th percentile (L; solid circle) and the region between H and L (M; open diamond). The statistical differences were calculated with Student’s paired t test. b Number of infusions in the three different groups. The statistical differences were calculated using Mann-Whitney U test