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Table 2 Clinical features and percentage of CD62L positive CD62LCD4+ T cells in 6 patients who discontinued the NTZ treatment

From: Natalizumab treatment reduces L-selectin (CD62L) in CD4+ T cells

  

During NTZ infusion

After NTZ withdrawal

 

JCV index

Number of infusion

CD62LCD4 (%)

Number of months

CD62LCD4 (%)

MRI

Relapse

Pt #1

3.498

40

5.65

5

49.07

Neg

None

Pt #2

2.488

16

16.34

3

56.48

Neg

None

Pt #3

2.696

20

35.44

4

32.21

Pos

1

Pt #4

2.034

71

44.50

3

42.32

Neg

None

Pt #5

1.366

66

15.83

4

56.59

Neg

None

Pt #6

2.304

32

41.18

3

27.78

Neg

None

  1. Neg unvaried number of lesions compared to previous MRI