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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes

Fig. 5

Functional recovery of inflammasome-deficient mice upon sciatic nerve injury. a Validation of the Nlrp3- and Nlrp6-deficient mice, using RT-qPCR. b Functional recovery of Nlrp3- and Nlrp6-deficient mice after peripheral nerve injury was determined by analyzing the SFI. Over a period of 7 weeks, Nlrp3 (n = 6) and Nlrp6 (n = 12) knock-out mice were compared to the control group (WT; n = 12). ***p ≤ 0.001 compared to the control group. c Validation of the ASC- and caspase-1/-11-deficient mice, using RT-qPCR. d Functional recovery of ASC- and caspase-1/-11-deficient mice after peripheral nerve injury was determined by analyzing the SFI. Over a period of 7 weeks, ASC- (n = 4) and caspase-1/11-deficient mice (n = 10) were compared to the control group (WT; n = 12)

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