Fig. 3

Osthole treatment reduces wound cavity size. a Representative images of hematoxylin and eosin-stained coronal sections at 3, 7, 14, and 21 dpi. The lesioned cortex is outlined in black. b Wound cavity area measurements. The area was smaller in osthole-treated mice than in untreated controls from 3 to 21 dpi. Measurements were obtained from six sections per mouse separated by 100 μm across the lesion, with six mice analyzed per time point. Data represent mean ± SD. *P < 0.05, **P < 0.01, vs. SWI control. Scale bar, 2.5 mm