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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Osthole confers neuroprotection against cortical stab wound injury and attenuates secondary brain injury

Fig. 6

Effect of osthole on gene expression in the injured brain. IL-6 mRNA expression was examined at 3 dpi, and Bax, Bcl-2, and caspase-3 levels were examined at 7 dpi. a mRNA expression as detected by RT-PCR. b Quantitative analysis of Bax/Bcl-2 ratio. c, d Quantitative analysis of caspase-3 and IL-6 mRNA levels. Osthole treatment reduced IL-6 and caspase-3 levels as well as Bax/Bcl-2 ratio relative to untreated controls. Data represent mean ± SD (n = 6 per group). ## P < 0.01 vs. naive control; *P < 0.05, **P < 0.01, vs. SWI control

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Journal of Neuroinflammation

ISSN: 1742-2094