Fig. 4

CS1 peptide inhibits Schwann cell activation. ERK1/2 immunoblotting in cultured Schwann cell lysates (11 μg total protein each) treated with CS1. Schwann cells were either starved in DMEM-1 % FBS for 24 h (a) or pre-treated with LPS (100 ng/ml) for 15 min (b) followed by CS1 (2.5 μg/ml) for 15 min or 1 h. The mean optical density of pERK1/2 to total ERK1/2 ratio based on four independent experiments (the graph, *p < 0.05)