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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: HMGB1 release triggered by the interaction of live retinal cells and uveitogenic T cells is Fas/FasL activation-dependent

Fig. 3

Faslpr mice do not develop ocular inflammation or release HMGB1 after IRBP-specific T cell transfer. Wt and Faslpr mice were injected with IRBP1–20-specific T cells and examined on day 15 (ac) post-injection. a Representative ocular histopathology with H & E staining of Wt and Faslpr eye sections, original magnification ×100. b Pathological score for the two groups (n = 12 mice) presented as the mean ± SEM. **p < 0.01 compared to Wt mice using the Mann-Whitney U test. c HMGB1 levels in the intraocular fluid (6 eye/group) measured by ELISA. **p < 0.01 compared to naïve mice by one-way ANOVA

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