Fig. 7
Fas-induced IL-1β release is not needed for tEAU induction. a Retinal explants collected from Wt mice were cultured for 6 h with medium (Ctrl) or medium containing 1 μg/ml of Jo2, then the culture supernatants were assayed for IL-1β by ELISA. *p < 0.05 compared to retinal explants treated with medium alone by one-way ANOVA. b, c Wt and IL-1RKO mice were injected with IRBP1–20-specific T cells and examined on day 21. b shows the pathological score for each group (n = 9 mice) presented as the mean ± SEM and c shows representative ocular histopathology with H & E staining, original magnification, ×100