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Table 1 Expression of cytokines and chemokines in aged brain

From: NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats

Gene symbol Gene name p value Fold change Function
Ccl19 Chemokine ligand 19 0.03 1.868 Basal leukocyte migration
Ccl2 Chemokine ligand 2 0.042 1.829 T lymphocytes/monocytes
Ccl3 Chemokine ligand 3 0.003 3.304 Monocytes/macrophages
Ccl4 Chemokine ligand 4 0.03 5.936 Natural killer cells/monocytes
Ccl5 Chemokine ligand 5 0.001 16.009 T cells/eosinophils
Cxcl10 Chemokine ligand 10 0.011 4.271 Multiple
Cxcl11 Chemokine ligand 11 0.001 3.302 T cells
Xcl1 Chemokine ligand 1 0.026 2.331 T cells
Il16 Interleukin 16 0.012 −1.951 CD4+ T cells
Tnf Tumor necrosis factor 0.029 1.494 Pro-inflammatory
Il1a Interleukin 1, alpha 0.009 2.458 Pro-inflammatory
Il1b Interleukin 1, beta 0.006 4.074 Pro-inflammatory
Il15 Interleukin 15 0.009 1.669 Pro-inflammatory
Ltb Lymphotoxin beta 0.043 1.583 Pro-inflammatory
Il24 Interleukin 24 0.001 −2.925 Anti-inflammatory
Il1rn Interleukin 1, receptor antagonist 0.001 5.644 Anti-inflammatory