Table 3 Expression of Wnt targets is decreased in aged hippocampus
From: NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats
Gene symbol | Gene name | p value | Fold change | Functional gene group |
|---|---|---|---|---|
Myc | Myelocytomatosis oncogene | 0.033 | −2.180 | Cell cycle |
Gdnf | Glial cell-derived neurotrophic factor | 0.038 | −2.744 | Neurotrophin |
Bmp4 | Bone morphogenetic protein 4 | 0.048 | −1.566 | TGF-β signaling |
Igf2 | Igf2 | 0.002 | −3.674 | Growth factor |
Fosl1 | Fos-like antigen 1 | 0.044 | −2.110 | Transcription factors |
Sox9 | SRY-box containing gene 9 | 0.016 | −2.325 | Transcription factors |
Sfrp2 | Secreted frizzled-related protein 2 | 0.042 | 1.517 | Wnt signaling |
Tle1 | Transducin-like enhancer of split 1) | 0.030 | 1.585 | Wnt signaling |