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Table 4 NT-020 diet increases expression of genes involved in regulating self-renewal

From: NT-020 treatment reduces inflammation and augments Nrf-2 and Wnt signaling in aged rats

Gene symbol

Gene name

p value

Fold change

Functional gene group

Gdnf

Glial cell-derived neurotrophic factor

0.020

2.231

Neurotrophin

Dlk1

Delta-like 1 homolog (Drosophila)

0.023

4.728

Differentiation and development

Id2

Inhibitor of DNA binding 2

0.002

−1.569

Differentiation and development

Fgf4

Fibroblast growth factor 4

0.015

1.899

Growth factor

Nanog

Nanog homeobox

0.016

1.809

Transcription factors

Sfrp2

Secreted frizzled-related protein 2

0.001

−2.685

Wnt signaling

Tle1

Transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

0.006

−2.000

Wnt signaling

Wisp1

WNT1-inducible signaling pathway protein 1

0.007

−2.166

Wnt signaling

Wnt3a

Wingless-type MMTV member 3A

0.038

−5.209

Wnt signaling