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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer’s disease

Fig. 2

Effect of MIF on tau hyperphosphorylation in the hippocampus. a Representative Western blots showing tau hyperphosphorylation at S199, T205, S396, and S404 in the hippocampi of WT and Mif −/− mice receiving ICV injection of STZ or saline. The levels of non-phosphorylated tau (Tau1) and total tau (Tau5) were also measured. Quantification of the immunoreactivity of representative Western blots, normalized against total tau (b) and β-actin (c). *p < 0.05, **p < 0.01 compared with WT mice receiving saline

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