Fig. 4

Fractin labeling for apoptosis. Immunolocalization of fractin (a specific apoptosis neoepitope derived from caspase-cleaved actin) in animals exposed to a 0.9 % sodium chloride (NaCl) or b lipopolysaccharide (LPS). Fractin labeling is intense in the corpus callosum of the LPS-treated animal. c Coronal apparent diffusion coefficient (ADC) maps of animals exposed to 0.9 % NaCl or LPS showing a significant restriction of diffusion in the corpus callosum (highlighted). d Anti-correlation between ADC and the natural logarithm of fractin expression in the corpus callosum. Adapted from [24]