Skip to main content

Advertisement

Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Sepsis-induced selective parvalbumin interneuron phenotype loss and cognitive impairments may be mediated by NADPH oxidase 2 activation in mice

Fig. 2

Sepsis-induced cognitive impairments were rescued by apocynin treatment. a, c No significant difference was observed in the total distance traveled in the open field test at days 13 and 29 among the four groups. b, d The time spent in the center of the arena was significantly decreased at day 13 but not at day 29 in the CLP + vehicle group compared with the sham groups, whereas apocynin treatment reversed the decrease in the CLP mice at day 13. e, f The freezing time to context and the freezing time to tone were significantly decreased in the CLP + vehicle group compared with the sham groups at day 14, whereas apocynin treatment reversed the decrease in the CLP mice. g, h No significant difference was observed in the freezing time to context or the freezing time to tone at day 30 among the four groups. Data are presented as mean ± SEM (n = 9–11). # p < 0.05 vs the sham groups, *p < 0.05 vs the CLP + vehicle group

Back to article page