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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Sepsis-induced selective parvalbumin interneuron phenotype loss and cognitive impairments may be mediated by NADPH oxidase 2 activation in mice

Fig. 6

Double-immunofluorescence staining to detect co-localization of PV and 8-OH-dG in the CA1 and CA3 regions of the hippocampus at day 14 after operation. a Representative images of PV (green) and 8-OH-dG (red) in the CA1 and CA3 regions of the hippocampus. b The PV immunoreactivity was decreased and the 8-OH-dG immunoreactivity was increased in the PV interneurons in the CA1 and CA3 regions of the hippocampus in the CLP + vehicle group compared with the sham groups, whereas apocynin treatment reversed these abnormities. Data are presented as mean ± SEM (n = 6). # p < 0.05 vs the sham groups; *p < 0.05 vs the CLP + vehicle group. Scale bar = 100 μm

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